Keto and Cognition

Can you really think better because of your diet?

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Idea

There is lots of anecdotal evidence for the benefit of the ketogenic diet on cognition in healthy adults.  Followers report attention, memory and other cognitive benefits, but to date all the evidence is anecdotal.  We are looking to change that.

If you are a follower of the Ketogenic diet (or even if you are not) please take the survey linked below.  Successful completion will put you in a drawing for a $50 gift card

What research is out there?

Check out some of the most recent literature on the ketogenic diet that inspired this project

Keto and health in rats

Kephart et al. 2017 The 1-week and 8-month effects of a ketogenic diet or ketone salt supplementation on multi-organ markers of oxidative stress and mitochondrial function in rats

Keto and metabolism in rats

Brownlow et al. 2017 Nutritional ketosis affects metabolism and behavior in Sprague-Dawley rats in both control and chronic stress environments

Keto and cognition in rats

Zhao et al. 2004 Detrimental effects of the ketogenic diet on cognitive function

Keto and sleep

Hallbook et al. 2007 Ketogenic diet improves sleep quality in children with therapy-resistant epilepsy

Keto and epilepsy in kids

Lambrechts et al. 2013 Ketogenic diet effects on cognition, mood, and psychosocial adjustment in children

Keto and sport

Paoli et al. 2015 The ketogenic diet and sport: A possible marraige

Keto and Health in mice

Poff et al. 2013 The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer

Ketones and inflamation

Youm et al. 2015 The ketone metabolite B-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

Keto and Alzheimers in mice

Brownlow et al. 2013 Ketogenic diet improves motor performance but not cognition in two mouse models of alzheimers pathology

Keto and memory in mice

Newman et al. 2017 Ketogenic diet reduces midlife mortality and improves memory in aging mice

Keto and strength

Wilson et al. 2017 The effects of ketogenic dieting on body composition, strength, power, and hormonal profiles in resistance training males

Timing of Keto diet for epilepsy

Kossoff et al. 2004 The impact of early versus late anticonvulsant reduction after ketogenic diet initiation

Keto and memory

Krikorian et al. 2012 Dietary ketosis enhances memory in mild cognitive impairment

Safety of keto

Kiens et al. 2015 Ketogenic diets for fat loss and exercise performance: Benefits and safety

Keto and Cycling

Zajac et al. 2014 The effects of a ketogenic diet on exercise metabolism and physical performance in off-road cyclists

Keto and seizures in rats

D'Agostino et al. 2013 Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats

Keto and gymnasts

Paoli et al. 2012 Ketogenic diet does not affect strength performance in elite gymnasts

Keto and memory in rats

Jiang et al. 2016 Ketogenic diet attenuates spatial and item memory impairment in pentylenetrazol-kindled rats

Keto and Endurance

Zinn et al. 2017 Ketogenic diet benefits body composition and well being by not performance in a pilot case study of New Zealand endurance athlets

Ketones and plasticiy in mice

Ciarlone et al. 2016 Ketone ester supplementation attenuates seizure activity and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model

Pulsifer et al.

2007

Effects of ketogenic diet on development and behavior: Preliminary report of a prospective study

Keto and epilepsy

Kinsman et al. 1992 Efficacy of the ketogenic diet for intractable seizure disorders: review of 58 cases

Keto and Taekwondo

Rhyu et al. 2014 The effect of weight loss by ketogenic diet on the body composition, performance-related physical fitness factors and cytokines of taekwondo athletes

Keto and depression

Murphy et al. 2004 The antidepressant properties of the ketogenic diet

Keto and sleep

Nikanorova et al. 2009 Ketogenic diet in the treatment of refractory continuous spikes and waves during slow sleep

Keto supplements in rats

Kesl et al. 2016 Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats